Flavones Occurring in Green Tea (Part 2)

Green tea and type 2 diabetes

Green tea and coffee consumption have been widely popular worldwide. These beverages contain caffeine to activate the central nervous system by adenosine receptor blockade, and due to the caffeine, addiction or tolerance may occur. In addition to this caffeine effect, green tea and coffee consumption have always been at the center of discussions about human health, disease, and longevity. In pa...

Green tea and type 2 diabetes mellitus

Tea is the most common beverage throughout the world. Green tea (Camellia sinensis) is full of flavonoids (1). This herbal drug has a lot of polyphenols, catechin epicatechin, epigallocatechin and epigallocatechin-3-gallate. It also contains other composites like saponins, caffeine, tannins, and some vitamins. Several different investigations have indicated that green tea has hypo-cholesterolae...

Green tea: a tea or a remedy?

Green tea polyphenol sensing

Green tea polyphenols have emerged over the past two decades as an important dietary factor for health promotion. There is considerable evidence that tea polyphenols, in particular (-)-epigallocatechin-3-gallate (EGCG) inhibit carcinogenesis. However, the mechanisms for the cancer-preventive activity of EGCG are not completely characterized and many features remain to be elucidated. Recently we...

Green tea gets molecular.

Green tea and its major polyphenolic flavonoid, epigallocatechin gallate (EGCG), have been credited with cancer chemopreventive activity for many years; the mechanism for this activity, however, has remained obscure. Now, as reported in this issue of the journal (beginning on page 1366), Urusova and colleagues showed direct binding of EGCG to the peptidyl prolyl cis/trans isomerase Pin1, which ...